Why PRS is a must in Immunohistochemistry?

Since IHC staining machine has never been properly calibrated for 80 years, we must need an on-slide control on each and single IHC staining

In addition to the reason above, we should also need a scale on each slide as a process quality indicator so as to comply with ISO 15189 - Laboratory Quality Management System for each IHC staining.  Afterall, IHC is considered a semi-quantitative test.

 

A map without a scale can never be a qualified map, neither does an IHC stained slide without a density scale. 

Please BE FAIR to pathologists and patients, use PROCESS RECORD SLIDE (PRS) for each IHC staining to safeguard the possibility of staining error which is done by a never ever properly calibrated stainer.